Sodium valproate is the sodium salt of Valproic acid. It has a role as a geroprotector. It contains a valproate.

Sodium valproate is a branched chain organic acid that is used to treat epilepsy and bipolar disorder. It’s occasionally used to prevent migraine headaches.

Sodium valproate is converted into its active form, valproate ion, in blood. Although the mechanism of action remains to be elucidated, valproate sodium increases concentrations of gamma-aminobutyric acid (GABA) in the brain, probably due to inhibition of the enzymes responsible for the catabolism of GABA. This potentiates the synaptic actions of GABA. Valproate sodium may also affect potassium channels, thereby creating a direct membrane-stabilizing effect.